Rpb1 CTD anticorps (pSer2, Ser2)

N° du produit ABIN2668539

Cet anticorps Rat Monoclonal détecte spécifiquement Rpb1 CTD dans WB, IF, ICC, ChIP, ChIP-seq et IP. Il présente une réactivité envers Humain et Souris et a été mentionné dans 6+ publications.

Aperçu rapide pour Rpb1 CTD anticorps (pSer2, Ser2) (ABIN2668539)

Antigène: Rpb1 CTD (RNA Polymerase II CTD)

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Rpb1 CTD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq), Immunoprecipitation (IP)

Clone: 3E10

Détail du produit anti-Rpb1 CTD anticorps

Épitope: pSer2, Ser2

Purification: Protein G Chromatography

Immunogène: This RNA pol II CTD pSer2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Antibodies in solution can be stored at -80 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-Rpb1 CTD (ABIN2668539)

Chung, Xu, Fuchs, Mund, Lange, Staege, Schubert, Bian, Dunkel, Eberharter, Regnard, Klinker, Meierhofer, Cozzuto, Winterpacht, Di Croce, Min, Will, Kinkley: "PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3." dans: eLife, Vol. 5, (2016) (PubMed).

Harlen, Trotta, Smith, Mosaheb, Fuchs, Churchman: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." dans: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).

Catania, Pidoux, Allshire: "Sequence features and transcriptional stalling within centromere DNA promote establishment of CENP-A chromatin." dans: PLoS genetics, Vol. 11, Issue 3, pp. e1004986, (2015) (PubMed).

Eifler, Shao, Bartholomeeusen, Fujinaga, Jäger, Johnson, Luo, Krogan, Peterlin: "Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts." dans: Molecular and cellular biology, Vol. 35, Issue 2, pp. 468-78, (2014) (PubMed).

Hintermair, Heidemann, Koch, Descostes, Gut, Gut, Fenouil, Ferrier, Flatley, Kremmer, Chapman, Andrau, Eick: "Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation." dans: The EMBO journal, Vol. 31, Issue 12, pp. 2784-97, (2012) (PubMed).

Chapman, Heidemann, Albert, Mailhammer, Flatley, Meisterernst, Kremmer, Eick: "Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7." dans: Science (New York, N.Y.), Vol. 318, Issue 5857, pp. 1780-2, (2007) (PubMed).

Détails sur Rpb1 CTD

Antigène: Rpb1 CTD (RNA Polymerase II CTD)

Autre désignation: RNA Pol II CTD

Poids moléculaire: 240 kDa

ID gène: 5430